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PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth
p53 acetylation is indispensable for its transcriptional activity and tumor suppressive function. However, the identity of reader protein(s) for p53 acetylation remains elusive. PBRM1, the second most highly mutated tumor suppressor gene in kidney cancer, encodes PBRM1. Here, we identify PBRM1 as a...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6925188/ https://ncbi.nlm.nih.gov/pubmed/31863007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13608-1 |
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