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Acetylation Is Crucial for p53-mediated Ferroptosis and Tumor Suppression

Although previous studies indicate that loss of p53-mediated cell cycle arrest, apoptosis, and senescence, does not completely abrogate its tumor suppression function, it is unclear how the remaining activities of p53 are regulated. Here we identified an acetylation site at lysine K98 in mouse p53 (...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Wang, Shang-Jui, Li, Dawei, Ou, Yang, Jiang, Le, Chen, Yue, Zhao, Yingming, Gu, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227654/
https://ncbi.nlm.nih.gov/pubmed/27705786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.022
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