Llwytho...

Acetylation Is Crucial for p53-mediated Ferroptosis and Tumor Suppression

Although previous studies indicate that loss of p53-mediated cell cycle arrest, apoptosis, and senescence, does not completely abrogate its tumor suppression function, it is unclear how the remaining activities of p53 are regulated. Here we identified an acetylation site at lysine K98 in mouse p53 (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Wang, Shang-Jui, Li, Dawei, Ou, Yang, Jiang, Le, Chen, Yue, Zhao, Yingming, Gu, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227654/
https://ncbi.nlm.nih.gov/pubmed/27705786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.022
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