Ferroptosis: A missing puzzle piece in the p53 blueprint?

Recent evidence indicates that canonical functions of p53 (i.e., apoptosis and growth arrest) are dispensable for p53-mediated tumor suppression. We have uncovered a novel function of p53 that contributes to tumor suppression through regulation of cystine metabolism, reactive oxygen species response...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Wang, Shang-Jui, Ou, Yang, Jiang, Le, Gu, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909446/
https://ncbi.nlm.nih.gov/pubmed/27314071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1046581
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