Loading...
Lysine succinylation and SIRT5 couple nutritional status to glutamine catabolism
The metabolic microenvironment of tumors is characterized by fluctuating and limited nutrient availability. To survive these conditions, cancer cell-intrinsic mechanisms sense and signal nutritional status. We describe how glutaminase (GLS) is destabilized by lysine succinylation and stabilized by t...
Saved in:
| Published in: | Mol Cell Oncol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2020
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199738/ https://ncbi.nlm.nih.gov/pubmed/32391426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1735284 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|