An EBNA3A-Mutated Epstein-Barr Virus Retains the Capacity for Lymphomagenesis in a Cord Blood-Humanized Mouse Model

Epstein-Barr virus (EBV) causes B cell lymphomas and transforms B cells in vitro. The EBV protein EBNA3A collaborates with EBNA3C to repress p16 expression and is required for efficient transformation in vitro. An EBNA3A deletion mutant EBV strain was recently reported to establish latency in humani...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Romero-Masters, James C., Ohashi, Makoto, Djavadian, Reza, Eichelberg, Mark R., Hayes, Mitchell, Zumwalde, Nicholas A., Bristol, Jillian A., Nelson, Scott E., Ma, Shidong, Ranheim, Erik A., Gumperz, Jenny E., Johannsen, Eric C., Kenney, Shannon C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Transformation and Oncogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199417/
https://ncbi.nlm.nih.gov/pubmed/32132242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02168-19
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