An EBNA3A-Mutated Epstein-Barr Virus Retains the Capacity for Lymphomagenesis in a Cord Blood-Humanized Mouse Model

Epstein-Barr virus (EBV) causes B cell lymphomas and transforms B cells in vitro. The EBV protein EBNA3A collaborates with EBNA3C to repress p16 expression and is required for efficient transformation in vitro. An EBNA3A deletion mutant EBV strain was recently reported to establish latency in humani...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Romero-Masters, James C., Ohashi, Makoto, Djavadian, Reza, Eichelberg, Mark R., Hayes, Mitchell, Zumwalde, Nicholas A., Bristol, Jillian A., Nelson, Scott E., Ma, Shidong, Ranheim, Erik A., Gumperz, Jenny E., Johannsen, Eric C., Kenney, Shannon C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199417/
https://ncbi.nlm.nih.gov/pubmed/32132242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02168-19
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