Differential Outcomes following Optimization of Simian-Human Immunodeficiency Viruses from Clades AE, B, and C

Simian-human immunodeficiency virus (SHIV) infection of rhesus monkeys is an important preclinical model for human immunodeficiency virus type 1 (HIV-1) vaccines, therapeutics, and cure strategies. SHIVs have been optimized by incorporating HIV-1 Env residue 375 mutations that mimic the bulky or hyd...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tartaglia, Lawrence J., Gupte, Siddhant, Pastores, Kevin C., Trott, Sebastien, Abbink, Peter, Mercado, Noe B., Li, Zhenfeng, Liu, Po-Ting, Borducchi, Erica N., Chandrashekar, Abishek, Bondzie, Esther Apraku, Hamza, Venous, Kordana, Nicole, Mahrokhian, Shant, Lavine, Christy L., Seaman, Michael S., Li, Hui, Shaw, George M., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199416/
https://ncbi.nlm.nih.gov/pubmed/32132241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01860-19
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