Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences

Simian-human immunodeficiency virus (SHIV) challenge stocks are critical for preclinical testing of vaccines, antibodies, and other interventions aimed to prevent HIV-1. A major unmet need for the field has been the lack of a SHIV challenge stock expressing circulating recombinant form 01_AE (CRF01_...

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Publicat a:PLoS Pathog
Autors principals: Tartaglia, Lawrence J., Chang, Hui-Wen, Lee, Benjamin C., Abbink, Peter, Ng’ang’a, David, Boyd, Michael, Lavine, Christy L., Lim, So-Yon, Sanisetty, Srisowmya, Whitney, James B., Seaman, Michael S., Rolland, Morgane, Tovanabutra, Sodsai, Ananworanich, Jintanat, Robb, Merlin L., Kim, Jerome H., Michael, Nelson L., Barouch, Dan H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743977/
https://ncbi.nlm.nih.gov/pubmed/26849216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005431
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