Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo

Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses. α-defensins are effector molecules of the innate immune response and have been shown to modulate natural infection with adenoviruses, but the majori...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Tartaglia, Lawrence J., Badamchi-Zadeh, Alexander, Abbink, Peter, Blass, Eryn, Aid, Malika, Gebre, Makda S., Li, Zhenfeng, Pastores, Kevin Clyde, Trott, Sebastien, Gupte, Siddhant, Larocca, Rafael A., Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936886/
https://ncbi.nlm.nih.gov/pubmed/31841560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008180
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