Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo

Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses. α-defensins are effector molecules of the innate immune response and have been shown to modulate natural infection with adenoviruses, but the majori...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Tartaglia, Lawrence J., Badamchi-Zadeh, Alexander, Abbink, Peter, Blass, Eryn, Aid, Malika, Gebre, Makda S., Li, Zhenfeng, Pastores, Kevin Clyde, Trott, Sebastien, Gupte, Siddhant, Larocca, Rafael A., Barouch, Dan H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936886/
https://ncbi.nlm.nih.gov/pubmed/31841560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008180
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