Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo

Adenoviral vectors have shown significant promise as vaccine delivery vectors due to their ability to elicit both innate and adaptive immune responses. α-defensins are effector molecules of the innate immune response and have been shown to modulate natural infection with adenoviruses, but the majori...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Tartaglia, Lawrence J., Badamchi-Zadeh, Alexander, Abbink, Peter, Blass, Eryn, Aid, Malika, Gebre, Makda S., Li, Zhenfeng, Pastores, Kevin Clyde, Trott, Sebastien, Gupte, Siddhant, Larocca, Rafael A., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936886/
https://ncbi.nlm.nih.gov/pubmed/31841560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008180
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