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Side chain effect in the modulation of α(v)β(3)/α(5)β(1) integrin activity via clickable isoxazoline-RGD-mimetics: development of molecular delivery systems
Construction of small molecule ligand (SML) based delivery systems has been performed starting from a polyfunctionalized isoxazoline scaffold, whose α(v)β(3) and α(5)β(1) integrins’ potency has been already established. The synthesis of this novel class of ligands was obtained by conjugation of link...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7198601/ https://ncbi.nlm.nih.gov/pubmed/32366988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64396-4 |
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