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Dehydro-β-proline Containing α(4)β(1) Integrin Antagonists: Stereochemical Recognition in Ligand–Receptor Interplay
[Image: see text] A novel class of dehydro-β-proline-containing peptidomimetics, designed to be effective as α(4)β(1) integrin ligands, has been developed on the basis of the fundamental requirements for the interactions of these transmembrane receptors with bioactive ligands. Dehydro-β-proline ring...
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| Publicado no: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468404/ https://ncbi.nlm.nih.gov/pubmed/26101577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00125 |
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