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DS‐70, a novel and potent α(4) integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs
BACKGROUND AND PURPOSE: Allergic conjunctivitis is an eye inflammation that involves the infiltration of immune cells into the conjunctiva via cell surface‐adhesion receptors, such as integrin α(4)β(1). These receptors interact with adhesion molecules expressed on the conjunctival endothelium and ma...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6151342/ https://ncbi.nlm.nih.gov/pubmed/30051467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14458 |
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