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Enhanced genome editing in human iPSCs with CRISPR-CAS9 by co-targeting ATP1a1
Genome editing in human induced pluripotent stem cells (iPSCs) provides the potential for disease modeling and cell therapy. By generating iPSCs with specific mutations, researchers can differentiate the modified cells to their lineage of interest for further investigation. However, the low efficien...
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| Publié dans: | PeerJ |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
PeerJ Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7197401/ https://ncbi.nlm.nih.gov/pubmed/32391204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9060 |
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