ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis

Heparin is the most widely prescribed biopharmaceutical in production globally. Its potent anticoagulant activity and safety makes it the drug of choice for preventing deep vein thrombosis and pulmonary embolism. In 2008, adulterated material was introduced into the heparin supply chain, resulting i...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Weiss, Ryan J., Spahn, Philipp N., Toledo, Alejandro Gómez, Chiang, Austin W. T., Kellman, Benjamin P., Li, Jing, Benner, Christopher, Glass, Christopher K., Gordts, Philip L. S. M., Lewis, Nathan E., Esko, Jeffrey D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196839/
https://ncbi.nlm.nih.gov/pubmed/32277030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920880117
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