ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis

Heparin is the most widely prescribed biopharmaceutical in production globally. Its potent anticoagulant activity and safety makes it the drug of choice for preventing deep vein thrombosis and pulmonary embolism. In 2008, adulterated material was introduced into the heparin supply chain, resulting i...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Weiss, Ryan J., Spahn, Philipp N., Toledo, Alejandro Gómez, Chiang, Austin W. T., Kellman, Benjamin P., Li, Jing, Benner, Christopher, Glass, Christopher K., Gordts, Philip L. S. M., Lewis, Nathan E., Esko, Jeffrey D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196839/
https://ncbi.nlm.nih.gov/pubmed/32277030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920880117
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