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ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis

Heparin is the most widely prescribed biopharmaceutical in production globally. Its potent anticoagulant activity and safety makes it the drug of choice for preventing deep vein thrombosis and pulmonary embolism. In 2008, adulterated material was introduced into the heparin supply chain, resulting i...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Weiss, Ryan J., Spahn, Philipp N., Toledo, Alejandro Gómez, Chiang, Austin W. T., Kellman, Benjamin P., Li, Jing, Benner, Christopher, Glass, Christopher K., Gordts, Philip L. S. M., Lewis, Nathan E., Esko, Jeffrey D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196839/
https://ncbi.nlm.nih.gov/pubmed/32277030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920880117
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