ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis

Heparin is the most widely prescribed biopharmaceutical in production globally. Its potent anticoagulant activity and safety makes it the drug of choice for preventing deep vein thrombosis and pulmonary embolism. In 2008, adulterated material was introduced into the heparin supply chain, resulting i...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Weiss, Ryan J., Spahn, Philipp N., Toledo, Alejandro Gómez, Chiang, Austin W. T., Kellman, Benjamin P., Li, Jing, Benner, Christopher, Glass, Christopher K., Gordts, Philip L. S. M., Lewis, Nathan E., Esko, Jeffrey D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196839/
https://ncbi.nlm.nih.gov/pubmed/32277030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920880117
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