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Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate
Heparan sulfate (HS) proteoglycans bind extracellular proteins that participate in cell signaling, attachment, and endocytosis. These interactions depend on the arrangement of sulfated sugars in the HS chains generated by well-characterized biosynthetic enzymes; however the regulation of these enzym...
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| 發表在: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159865/ https://ncbi.nlm.nih.gov/pubmed/33846619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00776-9 |
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