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Structure-based discovery of a small-molecule inhibitor of methicillin-resistant Staphylococcus aureus virulence

The rapid emergence and dissemination of methicillin-resistant Staphylococcus aureus (MRSA) strains poses a major threat to public health. MRSA possesses an arsenal of secreted host-damaging virulence factors that mediate pathogenicity and blunt immune defenses. Panton–Valentine leukocidin (PVL) and...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Liu, Jie, Kozhaya, Lina, Torres, Victor J., Unutmaz, Derya, Lu, Min
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196633/
https://ncbi.nlm.nih.gov/pubmed/32179646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012697
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