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Structure-based discovery of a small-molecule inhibitor of methicillin-resistant Staphylococcus aureus virulence
The rapid emergence and dissemination of methicillin-resistant Staphylococcus aureus (MRSA) strains poses a major threat to public health. MRSA possesses an arsenal of secreted host-damaging virulence factors that mediate pathogenicity and blunt immune defenses. Panton–Valentine leukocidin (PVL) and...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7196633/ https://ncbi.nlm.nih.gov/pubmed/32179646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012697 |
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