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Staphylococcus aureus Leukotoxin ED Targets The Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection
The Staphylococcus aureus leukotoxin ED (LukED) is a pore-forming toxin required for the lethality associated with bacteremia in murine models. LukED targets the chemokine receptor CCR5 to kill T lymphocytes, macrophages and dendritic cells. LukED also kills CCR5-deficient cells like neutrophils, su...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876884/ https://ncbi.nlm.nih.gov/pubmed/24139401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.09.005 |
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