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Staphylococcus aureus Leukotoxin ED Targets The Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection

The Staphylococcus aureus leukotoxin ED (LukED) is a pore-forming toxin required for the lethality associated with bacteremia in murine models. LukED targets the chemokine receptor CCR5 to kill T lymphocytes, macrophages and dendritic cells. LukED also kills CCR5-deficient cells like neutrophils, su...

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Bibliographische Detailangaben
Hauptverfasser: Reyes-Robles, Tamara, Alonzo, Francis, Kozhaya, Lina, Lacy, D. Borden, Unutmaz, Derya, Torres, Victor J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876884/
https://ncbi.nlm.nih.gov/pubmed/24139401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.09.005
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