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SGLT2 inhibition reduces atherosclerosis by enhancing lipoprotein clearance in Ldlr(−/−) type 1 diabetic mice

BACKGROUND AND AIMS: Leukocytosis, particularly monocytosis, has been shown to promote atherosclerosis in both diabetic and non-diabetic mouse models. We previously showed that hyperglycemia independently promotes monocytosis and impairs the resolution of atherosclerosis. Since patients with chronic...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Al-Sharea, Annas, Murphy, Andrew J., LA, Huggins, Y, Hu, Goldberg, Ira J., Nagareddy, Prabhakara R
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196281/
https://ncbi.nlm.nih.gov/pubmed/29518749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.02.028
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