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hERG K(+) Channels Promote Survival of Irradiated Leukemia Cells

Many tumor cells express highly elevated activities of voltage-gated K(+) channels in the plasma membrane which are indispensable for tumor growth. To test for K(+) channel function during DNA damage response, we subjected human chronic myeloid leukemia (CML) cells to sub-lethal doses of ionizing ra...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Palme, Daniela, Misovic, Milan, Ganser, Katrin, Klumpp, Lukas, Salih, Helmut R., Zips, Daniel, Huber, Stephan M.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194033/
https://ncbi.nlm.nih.gov/pubmed/32390841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00489
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