hERG K(+) Channels Promote Survival of Irradiated Leukemia Cells

Many tumor cells express highly elevated activities of voltage-gated K(+) channels in the plasma membrane which are indispensable for tumor growth. To test for K(+) channel function during DNA damage response, we subjected human chronic myeloid leukemia (CML) cells to sub-lethal doses of ionizing ra...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Palme, Daniela, Misovic, Milan, Ganser, Katrin, Klumpp, Lukas, Salih, Helmut R., Zips, Daniel, Huber, Stephan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194033/
https://ncbi.nlm.nih.gov/pubmed/32390841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00489
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