Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts

Despite substantial progress in treatment of T-cell acute lymphoblastic leukemia (T-ALL), mortality remains relatively high, mainly due to primary or acquired resistance to chemotherapy. Further improvements in survival demand better understanding of T-ALL biology and development of new therapeutic...

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Veröffentlicht in:Haematologica
Hauptverfasser: Agnusdei, Valentina, Minuzzo, Sonia, Pinazza, Marica, Gasparini, Alessandra, Pezzè, Laura, Amaro, Adriana Agnese, Pasqualini, Lorenza, Bianco, Paola Del, Tognon, Martina, Frasson, Chiara, Palumbo, Pietro, Ciribilli, Yari, Pfeffer, Ulrich, Carella, Massimo, Amadori, Alberto, Indraccolo, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193477/
https://ncbi.nlm.nih.gov/pubmed/31467126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.217687
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