An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma

Megakaryoblastic leukemia 1 (MKL1) is a coactivator of serum response factor and together they regulate transcription of actin cytoskeleton genes. MKL1 is associated with hematologic malignancies and immunodeficiency, but its role in B cells is unexplored. Here we examined B cells from monozygotic t...

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Udgivet i:Haematologica
Main Authors: Record, Julien, Sendel, Anton, Kritikou, Joanna S., Kuznetsov, Nikolai V., Brauner, Hanna, He, Minghui, Nagy, Noemi, Oliveira, Mariana M.S., Griseti, Elena, Haase, Christoph B., Dahlström, Jenny, Boddul, Sanjaykumar, Wermeling, Fredrik, Thrasher, Adrian J., Liu, Chaohong, Andersson, John, Claesson, Hans-Erik, Winqvist, Ola, Burns, Siobhan O., Björkholm, Magnus, Westerberg, Lisa S.
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193474/
https://ncbi.nlm.nih.gov/pubmed/31582539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.216317
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