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The biology of pediatric acute megakaryoblastic leukemia

Acute megakaryoblastic leukemia (AMKL) comprises between 4% and 15% of newly diagnosed pediatric acute myeloid leukemia patients. AMKL in children with Down syndrome (DS) is characterized by a founding GATA1 mutation that cooperates with trisomy 21, followed by the acquisition of additional somatic...

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Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Gruber, Tanja A., Downing, James R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551356/
https://ncbi.nlm.nih.gov/pubmed/26186939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-567859
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