Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin

This study aimed to clarify that organic anion transporters (OATs) mediate the drug–drug interaction (DDI) between imipenem and cilastatin. After co-administration with imipenem, the plasma concentrations and the plasma concentration-time curve (AUC) of cilastatin were significantly increased, while...

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Bibliografiske detaljer
Udgivet i:Asian J Pharm Sci
Main Authors: Zhu, Yanna, Huo, Xiaokui, Wang, Changyuan, Meng, Qiang, Liu, Zhihao, Sun, Huijun, Tan, Aiping, Ma, Xiaodong, Peng, Jinyong, Liu, Kexin
Format: Artigo
Sprog:Inglês
Udgivet: Shenyang Pharmaceutical University 2020
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193450/
https://ncbi.nlm.nih.gov/pubmed/32373203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.11.006
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