Organic anion transporters also mediate the drug–drug interaction between imipenem and cilastatin

This study aimed to clarify that organic anion transporters (OATs) mediate the drug–drug interaction (DDI) between imipenem and cilastatin. After co-administration with imipenem, the plasma concentrations and the plasma concentration-time curve (AUC) of cilastatin were significantly increased, while...

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Bibliografiska uppgifter
I publikationen:Asian J Pharm Sci
Huvudupphovsmän: Zhu, Yanna, Huo, Xiaokui, Wang, Changyuan, Meng, Qiang, Liu, Zhihao, Sun, Huijun, Tan, Aiping, Ma, Xiaodong, Peng, Jinyong, Liu, Kexin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Shenyang Pharmaceutical University 2020
Ämnen:
Research article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193450/
https://ncbi.nlm.nih.gov/pubmed/32373203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.11.006
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