Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

The emergence of artemisinin (ART) resistance in Plasmodium falciparum intra-erythrocytic parasites has led to increasing treatment failure rates with first-line ART-based combination therapies in Southeast Asia. Decreased parasite susceptibility is caused by K13 mutations, which are associated clin...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gnädig, Nina F., Stokes, Barbara H., Edwards, Rachel L., Kalantarov, Gavreel F., Heimsch, Kim C., Kuderjavy, Michal, Crane, Audrey, Lee, Marcus C. S., Straimer, Judith, Becker, Katja, Trakht, Ilya N., Odom John, Audrey R., Mok, Sachel, Fidock, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192513/
https://ncbi.nlm.nih.gov/pubmed/32310999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008482
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