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Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection

BACKGROUND: Congenital cytomegalovirus infection can lead to severe sequelae. When fetal infection is confirmed, we hypothesize that fetal treatment could improve the outcome. Maternal oral administration of an effective drug crossing the placenta could allow fetal treatment. Letermovir (LMV) and Ma...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Faure Bardon, Valentine, Peytavin, Gilles, Lê, Minh Patrick, Guilleminot, Tiffany, Elefant, Elisabeth, Stirnemann, Julien, Leruez-Ville, Marianne, Ville, Yves
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192425/
https://ncbi.nlm.nih.gov/pubmed/32353010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232140
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