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Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection

BACKGROUND: Congenital cytomegalovirus infection can lead to severe sequelae. When fetal infection is confirmed, we hypothesize that fetal treatment could improve the outcome. Maternal oral administration of an effective drug crossing the placenta could allow fetal treatment. Letermovir (LMV) and Ma...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Faure Bardon, Valentine, Peytavin, Gilles, Lê, Minh Patrick, Guilleminot, Tiffany, Elefant, Elisabeth, Stirnemann, Julien, Leruez-Ville, Marianne, Ville, Yves
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192425/
https://ncbi.nlm.nih.gov/pubmed/32353010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232140
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