MSH6 immunohistochemical heterogeneity in colorectal cancer: comparative sequencing from different tumor areas

Mismatch repair protein (MMR) immunohistochemistry is an important tool in screening for Lynch syndrome in colorectal cancer patients. Unusual staining patterns such as heterogeneous MSH6 staining have been reported in colorectal and endometrial cancers. We aim to better understand MSH6 staining het...

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Publicado en:Hum Pathol
Main Authors: Chen, Wei, Pearlman, Rachel, Hampel, Heather, Pritchard, Colin C., Markow, Michael, Arnold, Christina, Knight, Deborah, Frankel, Wendy L.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191319/
https://ncbi.nlm.nih.gov/pubmed/31783044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2019.11.003
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