Disruption of a RAC1-centred network is associated with Alzheimer’s disease pathology and causes age-dependent neurodegeneration

The molecular biological mechanisms of Alzheimer’s disease (AD) involve disease-associated crosstalk through many genes and include a loss of normal as well as a gain of abnormal interactions among genes. A protein domain network (PDN) is a collection of physical bindings that occur between protein...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Kikuchi, Masataka, Sekiya, Michiko, Hara, Norikazu, Miyashita, Akinori, Kuwano, Ryozo, Ikeuchi, Takeshi, Iijima, Koichi M, Nakaya, Akihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
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General Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191305/
https://ncbi.nlm.nih.gov/pubmed/31942999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz320
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