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Identification of Unstable Network Modules Reveals Disease Modules Associated with the Progression of Alzheimer’s Disease

Alzheimer’s disease (AD), the most common cause of dementia, is associated with aging, and it leads to neuron death. Deposits of amyloid β and aberrantly phosphorylated tau protein are known as pathological hallmarks of AD, but the underlying mechanisms have not yet been revealed. A high-throughput...

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Detalhes bibliográficos
Main Authors: Kikuchi, Masataka, Ogishima, Soichi, Miyamoto, Tadashi, Miyashita, Akinori, Kuwano, Ryozo, Nakaya, Jun, Tanaka, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858171/
https://ncbi.nlm.nih.gov/pubmed/24348898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076162
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