Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure

We previously established that global deletion of the enhancer of trithorax and polycomb (ETP) gene, Asxl2, prevents weight gain. Because proinflammatory macrophages recruited to adipose tissue are central to the metabolic complications of obesity, we explored the role of ASXL2 in myeloid lineage ce...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Zou, Wei, Rohatgi, Nidhi, Brestoff, Jonathan R., Moley, John R., Li, Yongjia, Williams, Jesse W., Alippe, Yael, Pan, Hua, Pietka, Terri A., Mbalaviele, Gabriel, Newberry, Elizabeth P., Davidson, Nicholas O., Dey, Anwesha, Shoghi, Kooresh I., Head, Richard D., Wickline, Samuel A., Randolph, Gwendalyn J., Abumrad, Nada A., Teitelbaum, Steven L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190927/
https://ncbi.nlm.nih.gov/pubmed/32310225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128687
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars