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ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1
Additional sex comb-like 1 (ASXL1) mutations are commonly associated with myeloid malignancies and are markers of aggressive disease. The fact that ASXL1 is necessary for myeloid differentiation raises the possibility it also regulates osteoclasts. We find deletion of ASXL1 in myeloid cells results...
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| Publicado no: | Blood Adv |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177649/ https://ncbi.nlm.nih.gov/pubmed/30266822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018018309 |
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