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PGC1β Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation

Osteoclasts are mitochondria-rich cells but the role of these energy-producing organelles in bone resorption is poorly defined. To this end, we conditionally deleted the mitochondria-inducing co-activator, PGC1β, in myeloid lineage cells to generate PGC1β(LysM) mice. In contrast to previous reports,...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Zhang, Yan, Rohatgi, Nidhi, Veis, Deborah J., Schilling, Joel, Teitelbaum, Steven L., Zou, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002881/
https://ncbi.nlm.nih.gov/pubmed/29521005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3398
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