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PGC1β Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation
Osteoclasts are mitochondria-rich cells but the role of these energy-producing organelles in bone resorption is poorly defined. To this end, we conditionally deleted the mitochondria-inducing co-activator, PGC1β, in myeloid lineage cells to generate PGC1β(LysM) mice. In contrast to previous reports,...
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| Publicado en: | J Bone Miner Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002881/ https://ncbi.nlm.nih.gov/pubmed/29521005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3398 |
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