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Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6

Lineage selective transcription factors (TFs) are important regulators of tumorigenesis, but their biological functions are often context dependent with undefined epigenetic mechanisms of action. In this study, we uncover a conditional role for the endodermal and pulmonary specifying TF GATA6 in lun...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Arnal-Estapé, Anna, Cai, Wesley L., Albert, Alexandra E., Zhao, Minghui, Stevens, Laura E., López-Giráldez, Francesc, Patel, Kiran D., Tyagi, Siddhartha, Schmitt, Earlene M., Westbrook, Thomas F., Nguyen, Don X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190573/
https://ncbi.nlm.nih.gov/pubmed/32157212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1246-z
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