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Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease
How stage-specific enhancer dynamics modulate gene expression patterns essential for organ development, homesostasis, and disease is not well understood. Here, we addressed this question by mapping chromatin occupancy of GATA4—a master cardiac transcription factor—in heart development and disease. W...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236193/ https://ncbi.nlm.nih.gov/pubmed/25249388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5907 |
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