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Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain

BACKGROUND: Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the epigenomic alterations and transcription factors (TFs) which underlie these...

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Foilsithe in:BMC Med Genomics
Main Authors: Cai, Wesley L., Greer, Celeste B., Chen, Jocelyn F., Arnal-Estapé, Anna, Cao, Jian, Yan, Qin, Nguyen, Don X.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060551/
https://ncbi.nlm.nih.gov/pubmed/32143622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-0695-0
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