miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction

Aging impairs the functions of human mesenchymal stem cells (MSCs), thereby severely reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play crucial roles in regulating the senescence of MSCs; however, the underlying mechanisms remain unclear. Here, we investigated t...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Hong, Yimei, He, Haiwei, Jiang, Guojun, Zhang, Hao, Tao, Wuyuan, Ding, Yue, Yuan, Dongsheng, Liu, Jing, Fan, Huimin, Lin, Fang, Liang, Xiaoting, Li, Xin, Zhang, Yuelin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189985/
https://ncbi.nlm.nih.gov/pubmed/32196916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13128
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