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Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
Edema stemming from leaky blood vessels is common in eye diseases such as age-related macular degeneration and diabetic retinopathy. Whereas therapies targeting vascular endothelial growth factor A (VEGFA) can suppress leakage, side-effects include vascular rarefaction and geographic atrophy. By cha...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7188482/ https://ncbi.nlm.nih.gov/pubmed/32312382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54056 |
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