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Genetic ablation of hematopoietic cell kinase accelerates Alzheimer’s disease-like neuropathology in Tg2576 mice
Microglial dysregulation, pertaining to impairment in phagocytosis, clearance and containment of amyloid-β (Aβ), and activation of neuroinflammation, have been posited to contribute to the pathogenesis of Alzheimer’s disease (AD). Detailed cellular mechanisms that are disrupted during the disease co...
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| Publicado no: | Mol Neurobiol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187907/ https://ncbi.nlm.nih.gov/pubmed/32146679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-01894-6 |
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