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S100a9 Knockdown Decreases the Memory Impairment and the Neuropathology in Tg2576 Mice, AD Animal Model

Inflammation, insoluble protein deposition and neuronal cell loss are important features in the Alzheimer's disease (AD) brain. To investigate the regulatory genes responsible for the neuropathology in AD, we performed microarray analysis with APP(V717I)-CT100 transgenic mice, an animal model o...

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Autori principali: Ha, Tae-Young, Chang, Keun-A, Kim, Jeong a, Kim, Hye-Sun, Kim, Seonghan, Chong, Young Hae, Suh, Yoo-Hun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809116/
https://ncbi.nlm.nih.gov/pubmed/20098622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008840
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