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Copper-Induced Upregulation of MicroRNAs Directs the Suppression of Endothelial LRP1 in Alzheimer’s Disease Model

Chronic exposure to copper and its dyshomeostasis have been linked to accelerated cognitive decline and potentially increasing risk for Alzheimer’s disease (AD). We and others have previously demonstrated that exposure to copper through drinking water significantly increased parenchymal amyloid-beta...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Hsu, Heng-Wei, Rodriguez-Ortiz, Carlos J, Lim, Siok Lam, Zumkehr, Joannee, Kilian, Jason G, Vidal, Janielle, Kitazawa, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592190/
https://ncbi.nlm.nih.gov/pubmed/30923833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz084
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