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Inflammatory cytokine, IL-1β, regulates glial glutamate transporter via microRNA-181a in vitro.
Glutamate overload triggers synaptic and neuronal loss that potentially contributes to neurodegenerative diseases including Alzheimer’s disease (AD). Glutamate clearance and regulation at synaptic clefts is primarily mediated by glial glutamate transporter 1 (GLT-1). We determined that inflammatory...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7325598/ https://ncbi.nlm.nih.gov/pubmed/29710703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170828 |
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