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Hydrogen Bond Surrogate Stabilization of β‑Hairpins
Peptide secondary and tertiary structure motifs frequently serve as inspiration for the development of protein–protein interaction (PPI) inhibitors. While a wide variety of strategies have been used to stabilize or imitate α helices, similar strategies for β-sheet stabilization are more limited. Syn...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187762/ https://ncbi.nlm.nih.gov/pubmed/30005156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00641 |
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