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Hydrogen Bond Surrogate Stabilization of β‑Hairpins

Peptide secondary and tertiary structure motifs frequently serve as inspiration for the development of protein–protein interaction (PPI) inhibitors. While a wide variety of strategies have been used to stabilize or imitate α helices, similar strategies for β-sheet stabilization are more limited. Syn...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Main Authors: Sawyer, Nicholas, Arora, Paramjit S.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187762/
https://ncbi.nlm.nih.gov/pubmed/30005156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00641
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