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Structural Considerations in the Fitness Landscape of a Virus
Viral fitness is determined by replication within hosts and transmission between them. We examine how pleiotropic mutations that have antagonistic effects (i.e., antibody evasion vs. receptor binding) on viral replication within hosts can impact viral immune escape in the host population. When the h...
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| Pubblicato in: | Mol Biol Evol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187634/ https://ncbi.nlm.nih.gov/pubmed/20194425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq056 |
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