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Structural Considerations in the Fitness Landscape of a Virus
Viral fitness is determined by replication within hosts and transmission between them. We examine how pleiotropic mutations that have antagonistic effects (i.e., antibody evasion vs. receptor binding) on viral replication within hosts can impact viral immune escape in the host population. When the h...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7187634/ https://ncbi.nlm.nih.gov/pubmed/20194425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq056 |
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