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Machine-learning a virus assembly fitness landscape

Realistic evolutionary fitness landscapes are notoriously difficult to construct. A recent cutting-edge model of virus assembly consists of a dodecahedral capsid with 12 corresponding packaging signals in three affinity bands. This whole genome/phenotype space consisting of 3(12) genomes has been ex...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dechant, Pierre-Philippe, He, Yang-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099058/
https://ncbi.nlm.nih.gov/pubmed/33951035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250227
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